| EdgeRelationType {SMRUCC.genomics.Analysis.GEARS.Graph} | .NET clr documentation |
基因调控图中边的关系类型
GEARS 将先验调控网络建模为异质图(heterogeneous graph), 不同类型的调控关系在消息传递时使用不同的变换矩阵与符号, 从而让模型能够学习到「激活边传递同向信号、抑制边传递反向信号」这样的生物学语义。
# namespace SMRUCC.genomics.Analysis.GEARS.Graph
export class EdgeRelationType extends Enum {
# 自环边(节点保留自身信息)
SelfLoop: EdgeRelationType = 0;
# 激活/正向调控(TF 促进靶基因表达)
Activation: EdgeRelationType = 1;
# 抑制/负向调控(TF 抑制靶基因表达)
Repression: EdgeRelationType = 2;
# 共表达边(由 control 表达谱相关性推断,无方向信息)
CoExpression: EdgeRelationType = 3;
}
SelfLoop: EdgeRelationTypeActivation: EdgeRelationTypeRepression: EdgeRelationTypeCoExpression: EdgeRelationType