run the in silico gene overexpression experiment on the given network model

overexpress {bnlearn}

R Documentation

run the in silico gene overexpression experiment on the given network model

Description

Usage

overexpress(bnlearn, geneNames);

Arguments

bnlearn

the trained network model object, which could be created by the bnlearn api or the GEARS::new. [as InsilicoPerturbationExperiment]

geneNames

a character vector of the gene id for run the overexpression experiment, one @T:SMRUCC.genomics.Analysis.BNLearn.Intervention.InterventionResult

env

[as Environment]




        Details

        

        Authors

        biosystem

        Value

        a vector of the InterventionResult perturbation result: the WildtypeMeans is the wildtype expression value of each gene, the MutantMeans is the expression value of each gene after the gene has been overexpressed, and the FoldChanges, PercentChanges, ZScores and IsSignificant data is the differential analysis result of the perturbation.
clr value class
InterventionResult

        Examples

        

        
        [Package bnlearn version 1.0.0.0 Index]